Genome maintenance, DNA repair, RNA processing, DNA replication stress, Chromatin Remodelling, Stress responses, Protein quality control, Genotoxins, Saccharomyces cerevisiae, Mutation Signatures.

Telomere and telomerase biology, inherited bone marrow failure syndromes, X-linked inheritance, cancer risk and therapeutics.

Research interests relate to the many ethical and social issues inherent within clinical practice and research in genetic and genomic medicine including: direct to consumer genetic testing; incidental/ secondary findings; and biobanks.

Computational biology, regulatory networks, genetics of complex traits, psychiatric genetics, machine learning in computational biology, genomics.