Our research bridges the molecular mechanisms of epigenetic regulation with the social and environmental determinants of human health to develop a comprehensive understanding of biological embedding of early life experiences

Proteomics, protein-protein interactions, protein isoform function, alternative splicing.

We study how transcriptional regulation affects metabolism and stress responses in C. elegans (worm), mice, and mammalian cells, to identify mechanisms that can be targeted in diseases such as cancers, diabetes, and neurodegenerative disorders.

Melanoma, Mouse models, Developmental Genetics.

Caring for people with (or with increased chance of) genetic differences, with a concentration on those that predispose to tumours or differences in sexual development. Clinical research projects that complement patient care. Educational leadership and faculty development.

Genetic control and manipulation of hemopoiesis. Stem Cell Regulation. Retroviral Gene Transfer. Transgenic Mice.

Stem cells, developmental control, telomere biology, self-renewal and genetic instability.