Using the latest next-generation sequencing technology and bioinformatics methods to sequence and analyse the genomes and transcriptomes of human breast cancers.

Activation of transcription factor complexes by signaling pathways with a focus on the Pi3K/Akt network. Protein/DNA interactions characterized by chromatin immunoprecipitation (ChIP), ChIP on chip (promoter and genome-wide arrays), gel shift and site-directed mutagenesis.

Chromosomal etiology of intellectual disability/autism and cancer, Molecular cytogenetics, Identification of subtle chromosomal abnormalities using whole genome arrays