The Center for Applied Neurogenetics (CAN; www.can.ubc.ca) at the University of British Columbia, Vancouver, Canada seeks two Postdoctoral Research Fellows to join a large interdisciplinary group studying the neurobiology / pathophysiology of genetic determinants of neurodegeneration. CAN is directed by Prof. Matt Farrer and the neuroscience group is under the direction of Dr. Austen Milnerwood. The Centre provides well-equipped, modern facilities and the opportunity to learn/apply a variety of molecular, cellular and physiological neuroscience techniques. The overall aim of the neurogenetic and neuroscience teams is to provide insights for novel therapeutic development to slow and/or prevent progressive neurological disorders.
The Fellowship opportunities relate to novel discoveries of pathogenic mutations in VPS35, RME-8 and LRRK2 linked to late-onset, familial Parkinson’s disease (Zimprich A. et al., 2004; Vilarino-Guell C. et al., 2011, 2014; reviewed by Lin Mk and Farrer MJ, 2014). A variety of models and tools have been generated and tested, including human iPSCs and conditional cre-loxP transgenic mice (Beccano-Kelly DA et al., 2014a,b; Munsie LN et al., 2014). Successful applicants will join a dedicated, experienced and highly motivated team of ~35 neurogeneticists and neurobiologists. The work is fast-paced and exciting, at the cutting edge of molecular insights into neurologic disease. Positions are initially available for one year with the possibility of annual extensions.
CAN is located in the vibrant neuroscience research atmosphere of the Djavadi Mowafaghian Centre for Brain Health at the University of British Columbia’s Point Grey Campus, situated within the temperate rain forest of Pacific Spirit Park. Surrounded by beaches and mountains, and boasting some of the worlds’ premier outdoor opportunities, Vancouver is consistently named as one of the top five worldwide cities for livability and quality of life.
QUALIFICATIONS:
Applicants must hold a Ph.D. or equivalent degree in a field directly relevant to translational neuroscience. Experience in biochemistry, molecular biology, cell biology or rodent behavior, neurochemistry and electrophysiology are required. Additionally applicants will have experience of either cellular biology / neurobiology (with emphasis on neuronal function) or expertise in biochemistry, protein purification and protein interactions. Successful applicants will have previously demonstrated research acumen, a track record of successful publication and clear potential for future success, in addition to:
- Broad knowledge of human molecular genetics, neurology and neuroscience
- Excellent communication skills including oral presentation at international conferences
- The ability to thrive in a high pressure, fast-paced and demanding team environment
- Drive and enthusiasm, to both lead and work as a member of a team
- Creativity, initiative and good judgment.
HOW TO APPLY
Please submit a full CV, three written references, and up to 3 representative publications to jobs@can.ubc.ca
UBC hires on the basis of merit and is committed to employment equity. All qualified persons are encouraged to apply. We especially welcome applications from members of visible minority groups, women, Aboriginal persons, persons with disabilities, persons of minority sexual orientations and gender identities, and others with the skills and knowledge to engage productively with diverse communities. Canadians and permanent residents of Canada will be given priority.