Pharmacogenomics

Lysosomal storage disease and disorders of sulfate transport.

Changes in specific genes that result in specific diseases, concentrating on Huntington disease and premature coronary artery disease.

Our research bridges the molecular mechanisms of epigenetic regulation with the social and environmental determinants of human health to develop a comprehensive understanding of biological embedding of early life experiences

Neurogenetics, Huntington disease and other triplet repeat disorders, transgenic/knockout mice, mouse models of human neurodegenerative disease, experimental therapeutics.

Pharmacogenomics of adverse drug reactions, genomics, personalized medicine.

Computational analysis of human genome sequence for the study of gene regulation and rare pediatric disorders.

Telomere and telomerase biology, inherited bone marrow failure syndromes, X-linked inheritance, cancer risk and therapeutics.