Location: CMMT, 950 West 28th Avenue, Vancouver, BC V5Z 4H4 Canada
Category: Research Associate, Goldowitz Laboratory
Duration: two-year term
Tenure: Full-time; term appointment, grant funded
Posting dates: 2014/03/06 – 2014/04/07
Deadline for application: 2014/04/07 4:30 pm PST
Description:
The Centre for Molecular Medicine and Therapeutics at the University of British Columbia seeks applications for a Research Associate in Developmental Neurobiology.
The successful candidate will lead research projects that use functional genomics and high-throughput research strategies to identify and validate gene candidates and gene networks critical for neuronal specification and differentiation in the developing mammalian cerebellum.
The Candidate is expected to manage and coordinate the efforts of lab members in conjunction with the Principle Investigator across three major research areas. Firstly, the candidate will lead the efforts of a collaborative team in the generation and analysis of high throughput gene expression data with a focus on temporal expression pattern analysis. Secondly, the candidate will establish model systems for in vitro and in utero gene delivery and analysis for the high throughput validation of candidate gene involvement in cerebellar development. Third, the candidate will use experimental embryological techniques to identify the cellular and molecular events disrupted in naturally occurring and genetically manipulated mutant strains of mice. This research will include collaborative elements with other research organizations and team members.
The research aims to identify and functionally characterize critical control genes in cerebellar neuronal development and to identify key temporal genetic regulatory networks that drive cerebellar developmental events.
Requirements:
The successful candidate will hold a Ph.D. in Developmental Neurobiology, Cell Biology, or related field and a minimum of 8 years related experience.
- The candidate will be expected to supervise and mentor postdoctoral fellows, graduate students and technicians in the laboratory, requiring experience and demonstration of strong project management skills and providing hands-on assistance to trainees.
- The candidate must have expertise in the areas of molecular genetics, cell biology, and histological analyses and be able to teach trainees and visiting scientists to utilize these techniques in their research programs.
- The candidate must be experienced in the development of functional genomics assays, DNA cloning, in vitro and in vivo systems gene delivery and analysis.
- The research requires expertise in RNA and protein methodologies, as well as histological techniques in assessing both RNA and protein expression.
- The candidate must have experience in primary neuronal cell culture analysis, and gene delivery in order to develop in vitro assays for candidate gene validation.
- The candidate must have practical experience and a keen working knowledge of laboratory animal assisted reproduction and mouse embryology necessary for carrying out studies of embryo manipulation in both in utero and in vitro systems.
- The candidate must have up-to-date knowledge of scientific tools and technologies of genomics and bioinformatics.
- The candidate should have a strong track record in scientific publications.
- The candidate should have demonstrated grant writing skills with a proven record of an ability to attract funding.
- The candidate should be highly collaborative, self-motivated, team-oriented, and have excellent communication skills.
Please email your cover letter and CV to Anita Sham (apsham@cmmt.ubc.ca) by the closing date April 7, 2014 at 4:30 pm PST. No phone calls, please.
UBC hires on the basis of merit and is strongly committed to equity and diversity within its community. We especially welcome applications from visible minority group members, women, Aboriginal persons, persons with disabilities, persons of minority sexual orientations and gender identities, and others with the skills and knowledge to productively engage with diverse communities. All qualified candidates are encouraged to apply; however Canadians and permanent residents will be given priority.