Medical Genetics/Drug Discovery Post-Doctoral Scientist

Location           Child and Family Research Institute

                          950 West 28th Avenue Vancouver, BC V5Z 4H4 Canada

Category          Postdoctoral Research Fellow

Group               Faculty – Postdoctoral Research Fellow

Department     Medical Genetics

Tenure             Full-time; Grant funded



A post-doctoral position is available at the University of British Columbia (Vancouver, Canada). This position is within, in the laboratory of Dr. Lorne Clarke and will focus on the development and evaluation of chaperone based therapy for Gaucher disease and GM2 gangliosidosis. This position is coupled to recently funded projects within the newly established GlycoNet network under the Networks of Centers of Excellence of Canada (NCE). This newly established Network will provide the right candidate with a strong and stable opportunity to work in a highly collaborative environment.



The Clarke lab has developed unique and novel transgenic models that are ideal for the evaluation of chaperone based therapy for Gaucher disease and GM2 gangliosidosis. Potential chaperones for each disorder have been identified through collaborative research projects with other investigators within GlycoNet including chemists and biochemists. The project will focus on the use of these unique transgenic models as a means to evaluate the biochemical and clinical impact of chaperone based therapies for these disorders. The work will include aspects of biochemical, pharmacologic, pathologic and clinical evaluation of drug effects. The ideal candidate will have an interest in developing novel approaches to evaluating this emerging therapeutic method.



This position is intended for a scientist within 3 years of completion of a PhD with demonstrated experience with use of murine models or other complex model systems, biochemical evaluation of tissues including enzyme and analyte analyses as well as pathologic evaluations. The ideal candidate will have experience in both biochemistry and pharmacological sciences, but applicants with a strong background in one domain may be considered if interest in interdisciplinary research is apparent.


How to Apply           

Please email your cover letter, resume and contact details of 3 potential references to Due to the number of resumes we receive, we are unable to confirm receipt of submissions over the phone, or provide the status of competitions except to those who are selected for an interview.

UBC hires on the basis of merit and is committed to employment equity. All qualified persons are encouraged to apply. UBC is strongly committed to diversity within its community and especially welcomes applications from visible minority group members, women, Aboriginal persons, persons with disabilities, persons of any sexual orientation or gender identity, and others who may contribute to the further diversification of ideas.