People

We study how transcriptional regulation affects metabolism and stress responses in C. elegans (worm), mice, and mammalian cells, to identify mechanisms that can be targeted in diseases such as cancers, diabetes, and neurodegenerative disorders.

Melanoma, Mouse models, Developmental Genetics.

We implement second generation sequencing technologies for the identification of mutations causing highly prevalent neurological diseases, with primary focus on multiple sclerosis, and characterize new models of human disease based on these discoveries for the development of novel and more effective treatments.

Research interests relate to the many ethical and social issues inherent within clinical practice and research in genetic and genomic medicine including: direct to consumer genetic testing; incidental/ secondary findings; and biobanks.