Past Defences
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2020 | 2019 |2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006
2005 | 2004 | 2003 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1995 |
2025
Doctoral Mufti, Kheireddin Pharmacogenomic study of vincristine-induced peripheral neuropathy in patients with pediatric cancers Jeffers, Kevin Characterization of the yeast Vps13 VAB domain in regard to its regulation of PxP adaptor recruitment and Vps13 function Master’s Illing, Hannah Placental DNA methylation patterns associated with pathology and maternal age Wu, Jiaqi Assessing the safety and efficacy of PODO83 and PODO447-ADC as cancer therapeutics Yu, Crystal Toward improving rare disease diagnosis : the rate of predicted splice variants reported from genome-wide sequencing and the discovery of RNA-binding protein with multiple splicing as a novel candidate gene causing a congenital malformation syndrome Findlay Black, Hailey Characterization of a synonymous DNA variant in the HTT gene and its effect on onset of Huntington disease Austin, Kennedy Evaluating empowerment in adolescents with a disability/chronic condition : a mixed-methods study Cameron, Makenna Fired up fat : role of the lysine acetyltransferases CBP and p300 in brown fat homeostasis and function
2024
Doctoral Porter, Vanessa Discovery of HPV-associated genomic alterations in cervical cancer Wainstein, Tasha Adolescent perspectives : genetic counselling, identity development, psychological adaptation, ableism, and peer attitudes in the context of a genetic condition Life, Benjamin Progranulin function and regulation in brain disease Holme, Sydney Mechanisms that regulate the activity of the NRas depalmitoylase ABHD17 Oppedisano, Anthony Functional analysis of the MUS81 structure selective endonuclease with dominant genetics Navarro Cobos, Maria Jose Combination of human and mouse XIST domains generates a minimal functional XIST Master’s Ashworth, Nolan Alternative polyadenylation at Mest Chen, Richard Optimization of APEX2 proximity labeling to identify protein interaction partners for cyclin-dependent kinase 12
2023
Doctoral Scott, Erika Elucidating genetic predictors for anthracycline-induced cardiotoxicity and cisplatin-induced ototoxicity in pediatric and adult cancer patients to improve patient treatment decisions Carlaw, Tiffany Therapeutic genome editing for the treatment of genetic diseases: Testing the safety and effectiveness of CRISPR/cas9 therapeutic base editing Cyrus, Sharri Polycomb Repressive Complex 2 Related Syndromes: Functional Studies of Human Gene Variants in Drosophila Shortill, Shawn Identification and Functional Analysis of the Endosomal vine complex in Saccharomyces cerevisiae Schaffner, Samantha Associations of DNA Methylation with Individual Differences in Parkinson’s Disease Susceptibility Dziurdzik, Samantha Membrane contact site targeting and functions of Vps13 and related bridging lipid transporters Thomson, Sarah Novel approaches for therapeutic modulation of gene expression in Huntington’s disease Gibson, Kristen Assessment of biological markers to aid subtype classification in pediatric primary systemic vasculitis Mirjalili, Zeinab Successful Gene Editing in a Novel Mouse Model of Aniridia Towards Prevention of Blindness Kumar, Arun Analytic models for carrier sense multiple access networks Akbari, Vahid Detecting DNA methylation using nanopore sequencing : from genome-wide analysis to haplotype-resolved and parent-of-origin phasing Master’s Jenkins, Kyle Simulating chromoanagenesis for tool development and testing Cheung, Chun Wai Characterization of DPP4⁺ fibroadipogenic progenitors in skeletal muscle Lin, Dorothy Dispersed measures of cord blood DNA methylation do not reflect third trimester bisphenol exposure Sabatino, Brendil Characterization of the transcriptomic response to acute starvation in the C. elegans hypodermis Adair, Bethany Development of a CRISPR gene correction strategy for aniridia employing a minimally humanized mouse embryonic stem cell-based disease model
2022
Doctoral Doering, Kelsie The Caenorhabditis elegans nuclear hormone receptor NHR-49 functions in stress response pathway regulation Eskandari-Nasab, Ebrahim Prosurvival role of CASPASE3 in normal and malignant human mammary cells Wang, Fangwu Characterization of the lympho-neutrophil/monocyte restriction process in human cells Ha, Amanda Functional characterization of Mest and its imprinted gametic differentially methylated region. Hasbullah, Jafar An investigation of the role of pharmacogenetics in the development and prevention of anthracycline-induced cardiotoxicity Master’s Dawo, Sebastian Salmonella Typhimurium Based Genome-Wide CRISPR/CAS 9 Knockout Screen to Study p16 Degradation Elazabbi, Nairuz Allele-specific expression differences in the mouse embryonic hindbrain following prenatal alcohol exposure Theberge, Emilie Investigating sex differences in the polygenic risk of major depressive disorder and shared associations with cardiovascular disease Horbach Marodin, Rafaela Genetic interactions between cohesin and DNA damage response pathways in Saccharomyces cerevisiae
Doctoral Amitzi, Leanne DDX11 Helicase as a Synthetic Lethal Cancer Therapy Target Pillsworth, Jessica Adult-Type Granulosa Cell Tumours of the Ovary: A Foxl2-Centric Disease Master’s Newman-Simmons, Avery Investigating the Genetic Contributions to Familial Intracranial Aneurysms in a First Nation from Northwestern British Columbia Riyadh, Omer Uncovering factors implicated in oncogenic NRAS modification by analyzing large scale functional genomic data sets Grant, Peter Investigating Trends in Out-of-Pocket Pay for Out-of-Province Genetic Testing in British Columbia
2020
Doctoral Refaeli, Ido Generation, characterization and optimization of mouse models for genetic glomerular disease Dixon-McDougall, Thomas Functionality of domains of XIST and their role in establishing chromosome inactivation Brown, Joshua Diverse functions of Rtt107 in the Saccharomyces cerevisiae DNA damage response Canals Hernaez, Diana Investigation of the Role of Podocalyxin in Cancer Progression and Its Potential as a Cancer Therapeutic Del Gobbo, Giulia Genomic Profiling in the Placenta: Toward a Greater Understanding of Genetic Variation Contributing to Placental Insufficiency and Fetal Growth Restriction Master’s Dever, Kristy A broader role for the RNAPII phosphatase, FCP1, in transcription regulation Lin, Jennifer The pharmacogenomics of hepatitis C: optimizing efficacy and safety on treatment Farag, Roula Molecular mechanisms of BAP1 mutations in uveal melanoma
2019 Doctoral Collins, Sorcha The role of the carnitine palmitoyltransferase 1A (CPT1A) p.P479L variant in Inuit infant and child health outcomes in Nunavut Kadhim, Alexandre Investigating the role of transcriptional coactivator MED15 in beta cell maturation Al Shekaili, Hilal Hamed Investigating vitamin B6-dependent epileptic encephalopathies in human patients and a mouse model Dixon, Katherine Molecular characterization and genetic diagnosis of cancer predisposition syndromes using genome and transcriptome sequencing Richard Albert, Julien Application of an allele-specific pipeline to study DNA methylation inheritance and dynamics in the early embryo Jones, Samantha Characterization of environmental and genetic factors in multiple-case lymphoid cancer families Tam, Annie S. The conserved role of RNA splicing factors in genome maintenance Urtatiz Gongora, Oscar Oncogenic GNAQ and BRAF in epidermal versus non-epidermal melanocytes Goodman, Sarah Contributions of intrinsic and environmental factors to early life DNA methylation Master’s Jain, Fagun Two novel genetically engineered mouse models for uveal melanoma with liver metastasis Kwan, Harwood An investigation into the non-coding genomic landscape and effects of chemotherapeutics in pre-treated advanced cancers Jensen, Kristoffer HP1-mediated transcriptional silencing of ERVs and genes in mouse embryonic stem cells Soundara Rajan, Jeffy Investigating mouse motor activity and learning behavior using quantitative trait locus (QTL) analysis to elucidate the genetic underpinnings of developmental coordination disorder (DCD) Gupta, Ishita Spatiotemporal characterisation of some transcriptional signatures in early cerebellar development Vermeulen, Michael Improving and estimating Y chromosome loss in blood and brain tissues using high-throughput sequencing
2018 Doctoral Barbaian, Artem Endogenous retroviruses drive transcriptional innovation in human cancer Peeters, Samantha Modelling human escape from X-chromosome inactivation in mouse Konwar, Chaini Molecular profiling of acute chorioamnionitis-affected placentas: insights into genomic variation underlying a common preterm birth condition Singh, Chaahat S. B. Mechanism underlying dysregulated cerebral vessel growth in Alzheimer’s disease Hickmott, Jack rAAV9 mediated PAX6 gene transfer temporarily reverses corneal epithelial thinning in a mouse model of aniridia Islam, Sumaiya Tissue-specific investigations on DNA methylation variation in human neurobiological diseases McEwen, Lisa DNA methylation variation across the human life course Wong, Chi Kin The role of p300 transcriptional coactivators in pancreatic beta cells Master’s Porter, Vanessa Targeting Autophagy in Chronic Myeloid Leukemia Through Inhibition of the Core Autophagy Protein ATG4B Shomer, Naomi A Regulatory Mechanism of Zinc Homeostasis Involving the Mediator Subunit MDT-15 and the Transcription Factor HIZR-1
2017 Doctoral Chen, Carol Interphase Histone H3 Serine 10 Phosphorylation in Mouse Embryonic Stem Cells Cohen, Ana Detailed Phenotyping and Next-Generation Sequencing for Characterization of Rare Overgrowth Syndromes Fam, Andrew Tyrosol-DNA Phosphodiesterase1 (TDP1): From Spinocerebellar Ataxia to Roles in Mitochondrial DNA Repair and Cancer Therapy Kay, Christopher Population Genetics and Allele-Specific Silencing of the Huntington Disease Mutation Lussier, Alexandre Andre Epigenetic Signatures of Prenatal Alcohol Exposure Wilson, Samantha Genetic and Epigenetic Profiling of Placental Insufficiency: Identifying Biomarkers of Preeclampsia and Intrauterine Growth Restriction Zhang, Peter Transcriptional Regulation in the Development of the Cerebellum and Cerebellar Granule Cells Zhang, Regan-Heng The Lysine Methyltransferase EHMT2/G9a in Mesenchymal Development Master’s Ellis, Samantha Introduction of the Antigen Presentation Machinery Using Novel Small Molecules Hitchcock, Emma Next Generation Sequencing to Determine a Genetic Cause of Familial Intracranial Aneurysms Little, Natasha Characterization of IAPLTR1 Subclasses and Bidirectional Promoter Activity: “Making Sense of it All” Reytan, Sivan Identification of Cancer Relevant Synthetic Genetic Interactions with Cohesin Mutations in Saccharomyces Cerevisiae Segovia Ugarte, Romulo Synthetic Hypermutation: Gene-Drug Mutation Rate Synergy Reveals a Translesion Selmer, Laura Intracranial Manifestations in Neurofibromatosis 1 Szetzo, Rochelle Telomere Position Effect in Embryonic Stem Cells: Heterogeneity, Imprinting, and Modifier Screen Turner, Kelly Assessment of a Potential Therapeutic Target in the Hedgehog Pathway for the Eradication of Primitive Chronic Myeloid Leukemia Cells Yuen, Michael Mapping Complex Genomic Translocations Using Strand-seq
2016 Doctoral Chung, George Chih Hsuen Genetic Determinants of Genome Stability and Crossover Distribution in the Nematode Caenorhabditis elegans Connolly, Colum Microglial Dysfunction Induced by Mutant Huntingtin Dastan, Jila Exome Sequencing for Understanding Phenotypic Variability in Subjects with 16p11.2 CNV Grants, Jennifer Roles of the Mediator Subunit CDK-8 in Developmental and Physiological Responses in Caenorhabditis elegans Kaurah, Pardeep Hereditary Diffuse Gastric: Cancer Risk and the Personal Cost of Preventative Surgery Ladha, Safia Impact of Caspase-6 Modulation on Huntington Disease Phenotypes in the YAC128 Mouse Model Trinh, Joanne Identification of Genetic Modifiers in Lrrks2 Parkinsonism Yeung, Joanna The Role of Pax6 and Wls in Rhombic Lip Compartmentation and Cerebellar Development Master’s de Goede, Olivia Identifying Epigenetic Associations with Cell Type and Gestational Age in the Neonatal Immune System Lee, Ka Young Functional Characterization of Gene Regulation by NHR-49 Pilsworth, Jessica Gene Expression and Mutation Profiles Define Novel Subclasses of Cytogenetically Normal Acute Myeloid Leukemia
2015 Doctoral DeSouza, Rebecca Characterization of the Huntingtin Gene Promoter and Huntingtin Transcriptional Regulation Heppner, Jonathan Early Disruption of the Extracellular Matrix in Murine Mucopolysaccharidosis I Lin, David Tse-Shen Characterization of Novel Regulatory Components in the Dynamic Protein Palmitolytion Cycle Liu, Sheng Transcriptional Repression of Retrotransposons in Mouse Germline Rothe, Katharina Characterization of Novel Therapeutic Targets in Chronic Meyloid Leukemia Tharmarajah, Grace The Role of Adamts9 in Melanoblast Migration and Modification of the Skin Proteome Thompson, Peter Transcriptional Silencing of Endogenous Retroviruses by the Novel Lysine Methytransferase Co-repressor hnRNP K Master’s Ang, Sidney Identification and Characterization of Dosage Mutator Genes in Saccharomyces cerevisiae Huff, Ryan Generation and Characterization of a Lysine (K)-specific Methyltransferase 2D Knockout Human Cell Line
2014 Doctoral Esmailzadeh, Sharmin The role of BIN1 in the Regulation of Cell Proliferation, Apoptosis and Tumor Formation in Cutaneous T-Cell Lymphoma Jett, Kimberly Vascular Function in Neurofibromatosis 1 Lee, Joshua Multiple Sclerosis in Asian Populations : The Genetic and Environmental Determinants of Variable Susceptibility and Clinical Profile Miller, Michelle Validation of Two Novel Mouse Models of Conditional Meis1 Deletion to Study Roles in Adult Mouse Hematopoiesis Poon, Anna Fong-Yee Genetic Architecture of Neurogenesis in the Adult Mouse Forebrain: Insights from Quantitative Trait Locus Analyses Master’s Billings, Raewyn Stimulating Human Tumour Heterogeneity using Cancer Cell Line Mixtures Greenwood, Talitha Gene Discovery in Individuals from Families Indicative of Mendelian Forms of Late-Onset Alzheimer Disease Huang, Jenny Li-Ying Ocular Melanocytes respond to Oncogenic GNAQQ209L differently compared to Epidermal and Dermal Melanocytes in Mice Kaur, Achint The Role of Sterol 12α- hydroxylase (Cyp8b1) in Glucose Homeostasis Lee, Jong Wook A Genome-Wide Association Study of Cisplatin-Induced Hearing Loss in Children Moshgabadi, Noushin Identification of Synthetic Cytotoxic Interactions to Improve the Efficacy of DNA Damaging Therapeutic Agents Tam, Annie Whole Genome Mutational Profiling of the Chemotherapeutic Agent Mitomycin C Ye, Xin Mapping a New Locus for Non-Syndromic Strabismus with High-Throughput Genome Analysis
2013 Doctoral Baradaran-Heravi, Alireza Schimke Immuno-osseous Dysplasia: Association of SMARCAL1 Mutations with Genetics and Environmental Disturbances of Gene Expression de Leeuw, Charles Development of Tools in Mouse for Future Gene Therapy: Promoters for the CNS, and Novel Expression Models of Neural Stem Cell Regulator, NR2E1 Hanna, Courtney Patterns of DNA Methylation on the Human X Chromosome and Use in Analyzing X-Chromosome Inactivation MacIsaac, Julia Developmental Consequences of Imprinted Transcription at the Mest Locus Mazarei, Gelareh Investigating the role of Indoleamine 2,3 dioxygenase in Huntington disease Master’s Blair, John DNA methylation studies of preeclamsia and related conditions Chapman, Andrew Transcriptional regulation of the XIST locus Jacob, Karen The function of the imprinted transcription factor ASCL2 in mouse trophoblast development Kelsey, Angela Mechanisms for XIST RNA cis-localisation Stepien, Katarzyna Prenatal Alcohol Exposure Programs Steady-State Gene Expression and the Gene Expression Response to Inflammation in the Adult Rat Brain Yoo, Janice The effects of cerebellar hemorrhage on the development of the postnatal cerebellum
2012 Doctoral Cotton, Allison Patterns of DNA Methylation on the Human X Chromosome and Use in Analyzing X-Chromosome Inactivation Earp, Madalene Genetic Studies to Discover Common Variants Associated with Epithelial Ovarian Cancer Risk and Variation in Age of Natural Menopause Kang, Martin Post-transcriptional Regulation of ABCA1 Minks, Jakub Role of XIST RNA and Its Interacting Protein Partners in Gene Silencing Semaka, Alicia Genetic Counselling Implications for Intermediate Allele Predictive Test Results for Huntington Disease Master’s Chowdhury, Miraj Tyrosyl-DNA Phosphodiesterase 1 (TDP1): A Rhabdomyosarcoma Therapeutic Target and Mitochondrial DNA Repair Enzyme Chun, Stella Identification and validation of CDK13 interacting proteins Fisher, Emily The Epidemiology of Huntington Disease in British Columbia Fornika, Dan Mitochondrial Genome Variation and Healthy Aging Lepage, Sarah Analysis of the Mechanism of Maintenance of the H3K27 Trimethylation Mark Using a Novel Chromatin Targeting System Yang, Christine DNA methylation demonstrates spread of X-chromosome inactivation to human transgenes
2011 Doctoral Burston, Helen Genome-wide Analysis of Endocytic Recycling inS. cerevisiae Deo, Mugdha Role of Nf1 Signaling in Regulating Pigmentation in Mice Lee, Connie The role of imprinted genes in mouse models of IUGR Leung, Danny Transcriptional Silencing of Endogenous Retroviruses: Interplay Between Histone H3K9 Methylation and DNA Methylation McLellan, Jessica A Cross Species Approach to Identify Potential Therapeutic Targets through Synthetic Lethal Interactions Oh-McGinnis, Rosemary Regulation of Genomic Imprinting in the Mouse Placenta Yuen, Ryan Epigenetics of Human Fetal and Placental Development Zahir, Farah The Pathogenicity of Copy Number Variants in Children with Intellectual Disability Master’s Brind’Amour, Julie Analysis of the Mechanism of Maintenance of the H3K27 Trimethylation Mark Using a Novel Chromatin Targeting System Decker, Michelle Telomere Length and Dynamics in Hutchinson-Gilford Progeria Syndrome Miceli, Katharine Who’s the Boss? An Investigation into the Complex Relationship between Endogenous Retroviruses and Nearby Genes Sekulovic, Sanja Analysis of the Mechanism of Maintenance of the H3K27 Trimethylation Mark Using a Novel Chromatin Targeting System
2010 Doctoral Alwan, Sura Risk Assessment of Birth Defects in Human Pregnancy Degeer, Donna Characterization of a Novel Fluorescent Reporter of Genomic Imprinting in the Mouse Gallo, Marco Misc/OCG is a New Stress Response Gene and Regulator of Apoptosis, Germline Stem Cell Proliferation and Insulin Secretion Jensen, Victor Novel Components of the Dauer Larva Developmental Signaling Pathway in Caenorhabditis elegans Schuetz, Johanna Genetic Variation in Lymphocyte Life and Death Genes and Risk of non-Hodgkin Lymphomas Jones, Meaghan XIST/Xist Induced Epigenetic Events in Somatic Cells Long, Michael Development of Strategies to Enhance the Contribution of Hematopoietic Cells to Skeletal Muscle Repair. Morrissy, Anca Bioinformatic Analysis of Cis-Encoded Antisense Transcription Pouladi, Mahmoud On the Modulation of Excitotoxicity as a Therapeutic Approach for the Treatment of Huntington Disease Thorogood, Nancy XIST/Xist Induced Epigenetic Events in Somatic Cells Vrljicak, Pavel Genomic Analysis of Embryonic Heart Development in the Mouse Young, Fiona The Biology and Expression of Huntingtin-Interacting Protein 14 Master’s Bourque, Danielle Imprinted Genes in the Placenta and Obstetrical Complications Degeer, Donna Characterization of a Novel Fluorescent Reporter of Genomic Imprinting in the Mouse Hirukawa, Alison The role of SHIP1 in modulating disease severity in the K/BxN serum transfer model of rheumatoid arthritis Huang, Jim The characterization of atm-1 in Caenorhabditis elegans Lohn, Zoe A New Role for the Tumour Suppressor, lin-35, During Meiotic Recombination in Caenorhabditis elegans Ngai, Tiffany The Low-density Lipoprotein Receptor Knock-out Mouse: A Model for the Study of Energy Balance Plamondon, Jenna Genetic and Epigenetic Factors in a Mouse Model for Multifactorial Cleft Lip Thiele, Jenny Generation and characterization of embryonic stem cell lines derived from the YAC128 mouse model of Huntington disease
2009 Doctoral Chang, Samuel Identification and characterization of cis-acting regulatory elements for human XIST Griffith, Malachi Methods for Transcript Variant Discovery and Alternative Expression Analysis – Application to the Study of Fluorouracil Resistance in Colorectal Cancer Haddon, Jamie Mast cells : homeostatic regulation, activation, gene expression, surface antigens, and role in allergic disease Lam, Karen The role of palmitoylation in endoplasmic reticulum transport and quality control of the yeast polytopic protein Chs3 Pugh, Trevor Analysis of primary human cancers: from single genes to whole transcriptomes Wong, Bibiana Evaluating the Effects of Variable NR2E1 Levels on Gene Expression, Behaviour, and Neural and Ocular Development Master’s Borrie, Adrienne A mutational screen of NR2E1 in patients with Aniridia, Peters’ Anomaly, and related eye disorders. Riendeau, Noemie Autism Spectrum Disorders: Identification of Novel Microdeletions and Microduplications and their Associated Phenotypes Tkac, Jan Detection of Telomeric DNA Circles in Human ALT Cells Using Rolling Circle Amplification Toub, Omid Initial characterization and Intracellular localization of two suppressors of position effect variegation in Drosophila melanogaster, S2214 and puckered
2008 Doctoral Bretherick, Karla Genetic factors in premature ovarian failure Griffith, Obi Identification of gene expression changes in human cancer using bioinformatic approaches Rouhi, Arefeh A role for epigenetic modifications in the maintenance of mouse Ly49 receptor expression Ryan, Jane A Genome-Wide Linkage Scan and Targeted Family-Based Association Analysis of Dyslexia Master’s Elves, Rachel Consequences of mitotic loss of heterozygosiy on genomic imprinting in mouse embryonic stem cells Kennah, Erin Identification of differentially expressed genes in AHL-1-mediated leukemic transformation in human cutaneous T-cell lymphoma Koochek, Maryam Sub-microscopic chromosomal imbalances in idiopathic autism spectrum disorder (ASD) Mazarei, Gelareh Identification of Novel Striatal-Enriched Transcripts and their Analysis in Huntington Disease Miller, Shelley Development of embryonic stem cells expressing endogenous levels of a fluorescent protein fused to the telomere binding protein TRF1 Wagner, Laura Silencing mutant huntington by RNA interference for the treatment of Huntington disease
2007 Doctoral Bakovic, Silvia Ex vivo expansion of hematopoietic stem cells for use in nonmyeloablative transplantation Brunham, Liam The impact of genetic variation in ABCA1 on cholesterol metabolism, atherosclerosis and diabetes Tarailo, Maja Spindle assembly checkpoint and chromosome stability in Caenorhabditis elegans Youds, Jillian Roles of the DOG-1 and JRH-1 helicase-like proteins in DNA repair in Caenorhabditis elegans Master’s Harbord, Sara X Chromosome Abnormalities in Breast and Ovarian Cancer
2006 Doctoral Graham, Rona In vivo characterization of caspase resistant huntingtin: Insights into the pathogenic mechanism of Huntington disease Kumar, Ravinesh Ex vivo expansion of hematopoietic stem cells for use in nonmyeloablative transplantation Mar, Lynn Role of TGIF in cell cycle control and establishment of laterality Nielsen, Julie The role of podocalyxin in adhesion and cell morphogenesis Tucker, Tracy Pathogenesis of neurofibromatosis 1 associated neurofibromas Yuen, Karen Identification and characterization of chromosome instability mutants in the yeast Saccharomyces cerevisiae and implications to human cancer Master’s Randall, Derrick Identification of a Serum Biomarker for Mucopolysaccharidosis Sipahimalani, Payal Variation in ATM and genetic susceptibility to non-Hodgkin lymphoma Quint, Desiree Aberrant Hypermethylation of Xq12 in Lymphoma Wu, Joyce YB-1 is a Downstream Component of the PI3K/Akt Signaling Pathway and Regulates EGFR in Breast Carcinoma: A Mechanism for Breast Cancer Growth
2005 Doctoral Cheng, Benjamin Identificaton of novel factors required for chromosome segregation in budding yeast Cheung, Iris Instability of G-rich DNA in Caenorhabditis elegans Gair, Jane Genetic mechanismss of nondisjunction in humans Gurevich, Rhonna Functional analysis of the NUP98- Topoisoerase 1 (NUP98-TOP1) fusion gene in the pathogenesis of leukemia Murray, Angus Functional genomics of the A600 locus in Leishmania mexicana Pleasance, Erin Identification and analysis of programmed cell death genes in Drosophila melanogaster and human cancer using bioinformatic analysis of gene expression data Van Raamsdonk, J. Characterization and treatment of mouse models in Huntington disease Master’s Schnerch, Angelique Analysis of Undifferentiated Human Embryonic Stem Cell Lines Using Serial Analysis of Gene Expression Hoscheit, Julia Multifactorial genetics of exencephaly in the SELH/Bc mouse strain Yen, Ziny Comparative sudies of X inactivation within Eutheria
2004 Doctoral Dickstein, Dara The Role of Inflammation and amyloid beta in Alzeimer Disease Pathology
2003 Doctoral Chopra, Vikramjit The HIP1 family of cytoskeletal-associated proteins Chow, Jennifer XIST and its role in X-chromosome inactivation Chu, Pak-Yan (Pat) Effect of c-kit and flt-3 overexpression on primitive hematopoietic cells Penaherrera, Maria X-chromosome inactivation pattern in human extraembryonic and fetal tissues Russell, Chris Transgenic expression of human alpha-L-iduronidase in mouse and characterization of the long term pathophysiology of murine alpha Wilhelm, Brian The genomic organization and transcriptional regulation of natural killer receptor genes Master’s Lee, Tsz Kin Bioinformatic analysis on NF1 transcriptional regulation
2002 Doctoral Anderson, Cathy Variable X inactivation of the human TIMP1 gene Faulkes, Sharlene Site-directed integration using the Cre/lox system in hematopoietic and embryonic stem cells Master’s Kwok, Ed XIST and macroH2A1.2 in hybrid cells
2001 Doctoral Szudek, Jacek Analysis of variable expressivity in Neurofibromatosis Parker, Jodey The Caenorhabditis elegans homologue of huntingtin interacting protein 1 has multiple roles in development
2000 Doctoral Moslehi, Roxana Genetic studies of ovarian cancer in Jewish women
1999 Doctoral Hodgson, John Production and characterization of YAC transgenic mice expressing the normal and mutant Huntington’s disease gene Bruskiewich, R. Genetic mapping, functional analysis and bioinformatics of Werner syndrome locus (WRN)
1998 Doctoral Gagne, Eric Identification and the relationship between mutations in the lipoprotein lipase gene, dyslipidemia and coronary heart disease Nelson, Tanya Molecular and genetic analysis of human 8p inversion duplication chromosomes Kowalski, Paul Novel genetic effects of a human endogenous retrovirus inserion
1997 Doctoral Ginzinger, David Lipoprotein lipase deficiency in a colony of domestic cats
1996 Doctoral Pawliuk, Robert Growth properties and genetic manipulation of murine hemopoietic stem cells
1995 Doctoral Biaoyang, Lin Cloning and characterization of genes in the proximal candidate region for the Huntington disease in mouse and human
